Refills the tank
Eating less starves the gut bacteria tied to digestion. Our marine polysaccharide + FOS blend feeds them back.
4.8 · 1,217 verified reviews
GLP-1 Companion
GLP-1 medication shrinks your appetite — but it also starves your microbiome. This prebiotic-led formula with 40 billion CFU refuels the gut bacteria that support digestion and comfort while your smaller meals change what reaches them. Support the gut, support your comfort.
- Formulated to support regularity
- Formulated for digestive comfort
- 96% reported better regularity and comfort
- Fully disclosed strains, third-party tested
- Supports a microbiome underfed by reduced food intake
- 40 billion CFU past stomach acid via BiCapsa® Technology
What's in your subscription
- 30-day money-back guarantee
- Flexible delivery and easy cancellation anytime
- Free shipping on subscriptions
The 30-Day Guarantee
If you don't feel more regular and comfortable within 30 days, we'll refund every penny.
How do I take it?
Take 2 capsules every morning with water — with or without food. That’s it. Your medication stays on its weekly schedule; Companion is the daily ritual beside it. Consistency matters more than timing: same time, every morning.
Can I take it alongside a GLP-1 medication?
Companion is a probiotic and prebiotic formula intended to support gut comfort — it doesn’t act on the GLP-1 pathway. As with any supplement, share the full ingredient list with your prescriber or pharmacist before combining it with any medication.
How long until I notice a difference?
Everyone’s different. The microbiome responds to consistency, so we recommend taking Companion daily for at least 4 weeks. Individual results vary.
Why do I need this if I already eat well?
Because on a GLP-1 you’re eating a fraction of what you used to — which means a fraction of the fiber and fermentable food your gut bacteria live on. Even a “perfect” small diet underfeeds the microbiome. Companion’s prebiotic blend replaces the fuel your meals no longer deliver.
What’s inside?
A 40 billion CFU blend of four research-backed strains — L. acidophilus La-14, B. lactis Bl-04, L. plantarum Lp-115 and L. paracasei Lpc-37 — protected by BiCapsa® marine delivery, plus a prebiotic duo of complex marine polysaccharide and fructooligosaccharide. Vegetable capsule, fully disclosed label.
Certificate of Analysis & Testing
Every minome product lot is third-party tested under our 5-Point Testing Program: presence of heavy metals in raw material, live CFU count in raw material, live CFU count at expiry in finished product, fill weight in finished product, and presence of heavy metals in finished product.
- Formulated by an MD
- Research-Backed Ingredients
- 3rd-Party Tested
- Made in the USA · cGMP
- Happiness Guaranteed
We look after what your medication can’t.
A prebiotic-led, 40 billion CFU formula that refuels the bacteria left starved by eating less, delivered past stomach acid so it actually reaches your gut.
See what’s inside
Supports regularity
Slowed digestion is the #1 GLP-1 complaint. 40 billion CFU are formulated to support everyday regularity.
Supports the adjustment
Four researched strains formulated to support digestive comfort as your body adjusts.
Built for the trip
Most probiotics degrade in stomach acid. BiCapsa® Technology is built to protect the 40 billion CFU.
What members told us
84%
Better DigestionOf members reported easier, smoother digestion
96%
Regular AgainOf members felt more regular within weeks
87%
Fuelled & ConfidentOf members felt better nourished while eating less
93%
Feeling GoodOf members reported improved overall wellbeing
Self-reported results from an independent consumer survey of 2,930 GLP-1 users, March 2026. Individual results vary. These are perceptions, not measured clinical outcomes.
Not a generic probiotic.
Drugstore probiotics were built for someone eating three full meals a day. That’s not you anymore — and your gut knows it. Companion is dosed, delivered, and built for the GLP-1 journey specifically.
Off the shelfGeneric probiotic
Purpose-builtGLP-1 Companion
Who it’s for
Who it’s for
Everyone — so no one in particular
You, eating less on a GLP-1
Fit with your meds
Fit with your meds
No idea you’re on one
Built around it — never replacing it
What it does
What it does
Vague “gut health”
Keeps you regular and comfortable
Prebiotics
Prebiotics
An afterthought, if any
Fuel your smaller meals stopped delivering
Getting there alive
Getting there alive
Most die in stomach acid
40B CFU past the acid, into your gut
What’s on the label
What’s on the label
Proprietary blends, inflated counts
Every strain named, ID’d, lab-tested
4.8 · 1,217 reviews
Real Reviews From GLP-1 Users on minome
1 day ago
“Three weeks after my first shot the bloating and constipation were unbearable. I started this every morning and after a few weeks my digestion felt much more comfortable. I won’t run out of it.”
Lisa R., 35Verified
1 day ago
“Smaller meals meant my digestion basically stalled. My dietitian recommended a prebiotic. A month into the morning ritual everything eased up and the bloating after eating is much better.”
Susan P., 55Verified
2 days ago
“The biggest change for me was comfort. The shot was working but my gut felt awful all the time. A few weeks on this and my mornings are predictable again — no more planning my day around my stomach.”
Sarah T., 38Verified
2 days ago
“Constipation was my biggest problem on the medication — I dreaded it. About four weeks into taking this every morning things finally felt more comfortable. Didn’t expect such a noticeable difference.”
Michael K., 56Verified
2 days ago
“The first few weeks on my GLP-1 were rough on my stomach. Adding this to my morning routine made the adjustment much more comfortable for me. I’ve recommended it to everyone in my support group.”
Jenna L., 41Verified
Prebiotics are the hero, not a footnote.
Most probiotics ship reinforcements to a gut with no food. Companion leads with the prebiotic fuel your smaller meals no longer provide — then backs it with 40 billion CFU of four named, research-backed strains, delivered alive.
Complex Marine Polysaccharide
Prebiotic — the lead ingredient
Supports a feeling of fullness while feeding gut bacteria to produce short-chain fatty acids that support natural appetite signaling.
Prebiotic heroMicrobiome fuelDaily refill
Fructooligosaccharide
FOS — prebiotic
Selectively feeds beneficial gut bacteria to support regularity and comfort, reinforcing the microbiome signaling behind balanced appetite.
Selective fuelFeeds good strainsPrebiotic duo
Lactobacillus Acidophilus
Strain La-14
One of the most-studied probiotic strains, supporting day-to-day digestive comfort and regularity as your routine shifts.
Digestive comfortDeeply researchedCore strain
Bifidobacterium Lactis
Strain Bl-04
Restocks the bifidobacteria population that drops when fiber intake falls, supporting regularity, a calmer gut, and the microbiome balance behind a steady appetite.
RegularityFiber-loss counterGut balance
L. Plantarum + L. Paracasei
Strains Lp-115 & Lpc-37
Two resilient strains that crowd the gut with the right bacteria and support a comfortable, well-defended gut lining.
Resilient strainsCrowding effectBlend complete
Non-GMO
40 Billion CFU
Doctor Formulated
3rd-Party Tested
GMP Certified
BiCapsa® Technology
Every Companion capsule is built to survive the trip.
A dual-layer BiCapsa® capsule is built to protect the 40 billion CFU from stomach acid on the way down.
40B
Outer capsule
A marine-based acid-resistant shell shields the live strains from stomach acid on the way down.
Inner capsule
Releases four probiotic strains lower in the gut — right where they’re intended to work.
Meet the Experts Behind The minome Formula
Our Scientific Advisory Board unites leading minds from Georgetown, Johns Hopkins, and the University of Victoria — collaborating to hold every minome formula to the cutting edge of metabolic and microbiome science.
Dr. Marc R. Blackman, MD
Endocrinologist & Physician-Scientist, Professor of Medicine at Georgetown & Johns Hopkins
Dr. Nancy M. Sherwood
PhD, Comparative Neuroendocrinologist, Professor of Biology at the University of Victoria
Harmandeep Singh, MD
Board Certified Physician, Metabolism & Anti-Aging Specialist
How does GLP-1 Companion work alongside my medication?
It doesn’t mimic, replace, or compete with your medication — it cares for the part of you the medication doesn’t. The shot does the appetite work; Companion refeeds the gut bacteria that smaller meals leave starving, with a prebiotic blend plus 40 billion CFU of four named strains. Comfort and regularity are the outcome — not weight loss. Your medication owns that.
Can I take it alongside a GLP-1 medication?
Companion’s probiotics and prebiotics aren’t designed to act on the GLP-1 pathway. As with any supplement, share the full ingredient list with your prescriber or pharmacist before combining it with any medication.
When will I notice a difference?
Everyone’s different. The microbiome responds to consistency, so we recommend taking Companion daily for at least 4 weeks. A steady daily routine is what matters most. Individual results vary.
Why lead with prebiotics instead of just more probiotic strains?
Because the problem on a GLP-1 isn’t a lack of bacteria — it’s a lack of food for them. Eating 30–40% less means 30–40% less fermentable fuel arriving in your gut. Probiotics are reinforcements; prebiotics are rations. Companion sends both, with the rations leading.
Is it vegetarian, and are there allergens?
Yes — the capsule is hypromellose (a vegetable capsule), with rice maltodextrin and L-leucine as the only other ingredients. The BiCapsa® delivery system and prebiotic are marine-derived; if you have a fish or shellfish allergy, check with your healthcare provider first.